Evidence map›Paper›PMID 40143855›Full record

ArticleFrontiers in microbiology2025

TcSR62, an RNA-binding protein, as a new potential target for anti-trypanocidal agents.

Analía G Níttolo, Agustina M Chidichimo, Ana L Benacerraf, Timothy Cardozo, M Clara Corso, Valeria Tekiel, Javier G De Gaudenzi, Gabriela Vanesa Levy

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Analía G NíttoloComisión de Investigaciones Científicas de la Provincia de Buenos Aires (CIC), La Plata, Argentina.
Agustina M ChidichimoInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martin, Argentina.
Ana L BenacerrafNYU Langone Health, New York University School of Medicine, New York, NY, United States.
Timothy CardozoNYU Langone Health, New York University School of Medicine, New York, NY, United States.
M Clara CorsoInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martin, Argentina.
Valeria TekielInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martin, Argentina.
Javier G De GaudenziInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martin, Argentina.
Gabriela Vanesa LevyInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martin, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trypanosomatids are parasites of health importance that cause neglected diseases in humans and animals. Chagas' disease, caused by

Indexed as

Chagas diseasedrug repurposingIC50molecular modelingresazurinsorafenib tosylatetreatmentTrypanosoma cruzi

Identifiers

PMID40143855
PMCPMC11936972

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.