Evidence map›Paper›PMID 40143967›Full record

ArticleFrontiers in cell and developmental biology2025

Cerebrospinal fluid-contacting neurons: a promising source for adult neural stem cell transplantation in spinal cord injury treatment.

Zhangrong Luo, Zeyu Shangguan, Liang Cao, Yi Zhang, Qizhe Li, Xuexing Shi, Jiangquan Fu, Chunqing Wang, Xiaowei Dou, Wei Tan and 1 more

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhangrong Luo *Department of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Zeyu Shangguan *Department of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Liang CaoDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Yi ZhangDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Qizhe LiDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Xuexing ShiDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Jiangquan FuDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Chunqing WangDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Xiaowei DouClinical Research Center, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Wei TanDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Qing LiDepartment of Emergency, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplantation of adult neural stem cells (NSCs) is regarded as one of the most promising approaches for treating spinal cord injury (SCI). However, securing a sufficient and reliable source of adult NSCs remains one of the primary challenges in applying this method for SCI treatment. Cerebrospinal fluid-contacting neurons (CSF-cNs) act as adult NSCs and can be substantially expanded

Indexed as

cell transplantation therapycerebrospinal fluid-contacting neurons (CSF-cNs)motor function recoveryneural stem cellsspinal cord injury (SCI)

Identifiers

PMID40143967
PMCPMC11936957

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.