Evidence map›Paper›PMID 40144043›Full record

ArticleDigital health

DANCE Rehabilitation EXperience (DANCEREX-DTx): Protocol for a randomized controlled trial on effectiveness of digital therapeutics in chronic neurological disabilities.

Francesca Borgnis, Valeria Blasi, Olivia Realdon, Fabrizia Mantovani, Maria Cotelli, Rosa Manenti, Elena Campana, Viviana Lo Buono, Silvia Marino, Petar Aleksandrov Mavrodiev and 5 more

Abstract read
In one paragraph

Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Francesca BorgnisIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0001-8237-6164
Valeria BlasiIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0002-8395-0452
Olivia RealdonDepartment of Human Sciences for Education, Università degli Studi di Milano-Bicocca, Milan, Italy.ORCID https://orcid.org/0000-0002-7879-4723
Fabrizia MantovaniDepartment of Human Sciences for Education, Università degli Studi di Milano-Bicocca, Milan, Italy.ORCID https://orcid.org/0000-0003-4772-9109
Maria CotelliNeuropsychology Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID https://orcid.org/0000-0003-3208-3798
Rosa ManentiNeuropsychology Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID https://orcid.org/0000-0002-5955-2323
Elena CampanaNeuropsychology Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID https://orcid.org/0000-0003-1350-3291
Viviana Lo BuonoIRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.ORCID https://orcid.org/0000-0001-8027-6098
Silvia MarinoIRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.ORCID https://orcid.org/0000-0002-1088-6808
Petar Aleksandrov MavrodievIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0002-1895-9020
Marina SaresellaIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0002-2295-3043
Pietro Davide TrimarchiIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0003-3282-5261
Margherita AlberoniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0001-6630-9092
Maria Pia AmatoIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0003-3325-3760
Francesca BaglioIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID https://orcid.org/0000-0002-6145-5274

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Rehabilitation is an important player in preventing and reducing the high impact of disability on everyday functioning in chronic neurological diseases (CNDs), especially if timely, intensive, and multidimensional. However, to date, rehabilitation is often a service accessible only to a few people, and the issue of a progressive decrease in treatment adherence still remains to be addressed. This study protocol describes an RCT whose aim is to test the effectiveness in terms of adherence of DANCE Rehabilitation EXperience (DANCEREX-DTx), a new digital therapeutic solution which combines a holistic, multidimensional program based on dance and music with an innovative motivational system. Methods: The randomized, single-blind, controlled trial will involve 192 patients with CNDs from three rehabilitation centers in Italy. Participants will be randomized (with an allocation ratio of 2:2:1) into three interventions: (1) DANCEREX treatment, (2) multidimensional dance-based program, and (3) educational program. Groups will be assessed at the baseline (T0), after intervention (T1-after 12 weeks), and after six months from enrollment (T2). The primary outcome will be treatment adherence in terms of the number of drop-outs and the percentage of attended sessions on the total prescribed. Moreover, a multifaceted evaluation, including quality of life and clinical/functional measures, will be conducted at each time-point. Surrogate measures (neuroimaging and neurobiological) will be collected at T0 and T1. Finally, usability and acceptability will be assessed at T1. Results: We expect the validation, in terms of usability, acceptability, and effectiveness of DANCEREX-DTx as an innovative rehabilitation program able to respond in a sustainable way to the great need for rehabilitation of people with CNDs. Conclusion: With DANCEREX-DTx, we aspire to change the hospital-centered paradigm of rehabilitation care to bring it to the patients' homes, making them active in their treatment path and promoting motivation and adherence to treatment from the initial stages of the disease.

Indexed as

dementiadigital therapeuticsmotivationmultiple sclerosisRehabilitation

Identifiers

PMID40144043
PMCPMC11938902

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.