Detection Rate of Diabetic Retinopathy Before and After Implementation of Autonomous AI-based Fundus Photograph Analysis in a Resource-Limited Area in Belize.

Purpose: To evaluate the use of an autonomous artificial intelligence (AI)-based device to screen for diabetic retinopathy (DR) and to evaluate the frequency of diabetes mellitus (DM) and DR in an under-resourced population served by the Stanford Belize Vision Clinic (SBVC). Patients and Methods: The records of all patients from 2017 to 2024 were collected and analyzed, dividing the study into two time periods: Pre-AI (before June 2022, prior to the implementation of the LumineticsCore Results: A total of 1897 patients with a mean age of 47.6 years were included. The gradability of encounters by the AI device was 89.1%. The frequency of DR detection increased significantly in the Post-AI period (55/639) compared to the Pre-AI period (38/1258), including during the COVID-19 pandemic. The mean age of DR diagnosis was significantly lower in the Post-AI period (44.1 years) compared to Pre-AI period (60.7 years) among DM negative patients. There was a significant association between having DR and hypertension. Additionally, the detection rate of DM increased in the Post-AI period compared to Pre-AI period. Conclusion: Autonomous AI-based screening significantly improves the detection of patients with DR in areas with limited healthcare resources by reducing dependence on on-field ophthalmologists. This innovative approach can be seamlessly integrated into primary care settings, with technicians capturing images quickly and efficiently within just a few minutes. This study demonstrates the effectiveness of autonomous AI in identifying patients with both DR and DM, as well as associated high-burden diseases such as hypertension, across various age ranges.