Evidence mapPaperPMID 40144416Full record

ReviewCureus2025

Adolescent Fentanyl Use: Toxicological Risks, Epidemiological Trends, and Public Health Strategies.

Matteo Antonio Sacco, Saverio Gualtieri, Agostinho Santos, Bárbara Mendes, Isabella Aquila

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matteo Antonio SaccoDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, ITA.
Saverio GualtieriDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, ITA.
Agostinho SantosDepartment of Legal Medicine and Forensic Sciences, Faculty of Medicine, University of Porto, Porto, PRT.
Bárbara MendesDepartment of Forensic Medicine, Instituto Nacional de Medicina Legal e Ciencias Forenses, Porto, PRT.
Isabella AquilaDepartment of Medical and Surgical Sciences, Institute of Legal Medicine, Magna Graecia University, Catanzaro, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fentanyl has become a critical public health concern due to its increasing presence in illicit drug markets and its role in the rising number of opioid-related fatalities, particularly among adolescents. This study examines the toxicological properties of fentanyl, its accessibility through online platforms, and the behavioral factors contributing to its misuse in adolescent populations. Key findings highlight the high risk of overdose due to fentanyl's potency, especially when combined with substances such as alcohol and benzodiazepines. Epidemiological data reveal a dramatic surge in adolescent fentanyl-related deaths, exacerbated by counterfeit prescription drugs and a lack of awareness regarding its extreme potency. The study also explores prevention and intervention strategies, including public health education, harm reduction approaches, and policy recommendations aimed at mitigating the growing crisis. Addressing this issue requires a multifaceted approach, integrating medical, social, and legislative efforts to protect vulnerable adolescent populations.

Indexed as

adolescentdrug abusefentanylillicit drugyoung adult behavior

Identifiers

PMID40144416
PMCPMC11939030

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.