ArticleFrontiers in psychiatry2025
Higher levels of total cholesterol/high-density lipoprotein cholesterol ratios are associated with an increased risk of suicidal behavior in children and adolescents with depressive disorders.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Immune-metabolic dysregulation and suicide risk in adolescents with major depressive disorder: a cross-sectional study.BMC psychiatry · 2026Article
- Factors influencing suicidal ideation in Chinese adolescents with first-episode depressive disorder: a cross-sectional study.BMC psychology · 2026Article
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9 authors.
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Abstract
Objective: To explore the prevalence of suicidal ideation (SI) and suicidal attempt (SA) in inpatients with childhood and adolescent depressive disorders and the relationship between triglyceride/high-density lipoprotein cholesterol (TG/HDL-C), total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) ratios and SI, SA. Methods: A study was conducted involving 515 pediatric patients diagnosed with depressive disorders at the Third People's Hospital of Fuyang. This research primarily focused on gathering basic demographic and clinical data. Through employing methods such as correlation analysis and logistic regression, the study aimed to identify factors linked to SI and SA among these individuals. Results: The prevalence of SI and SA was 20.0% (103/515) and 9.1% (47/515). Binary logistic regression highlighted several independent predictors for SI. A notable increase in the likelihood of SI was observed with an increase in the number of hospitalizations (Odds Ratio [ Conclusion: These findings suggest that monitoring lipid profiles, particularly the TC/HDL-C ratio, alongside careful management of antidepressant dosages and close observation of depressive symptoms, could be crucial in mitigating suicidal risks among this vulnerable population.
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