Evidence mapPaperPMID 40145976Full record

ArticleNeural regeneration research2026

The role of the peripheral immune system in mediating axonal dysfunction in early-stage amyotrophic lateral sclerosis: An age- and sex-based analysis.

Zhuoya Wang, Wen Cao, Lu Chen, Shuo Zhang, Lu Tang, Wenjuan Cui, Mingjun Kong, Ling Yu, Dongsheng Fan, Wei Zheng

Abstract read
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Huoling Shengji granule in amyotrophic lateral sclerosis: A multicenter, randomized, double-blind, riluzole-controlled trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Role of lipocalin-2 in amyotrophic lateral sclerosis.Frontiers in aging neuroscience · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhuoya WangDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Wen CaoDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Lu ChenDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Shuo ZhangDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Lu TangDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Wenjuan CuiDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Mingjun KongDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Ling YuDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Dongsheng FanDepartment of Neurology, Peking University Third Hospital, Beijing, China.ORCID 0000-0002-3129-9821
Wei ZhengDepartment of Neurology, Peking University Third Hospital, Beijing, China.ORCID 0009-0008-0445-716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amyotrophic lateral sclerosisaxonal degenerationcompound muscle action potentialdisease progressionmediation analysisneutrophilneutrophil to lymphocyte ratioperipheral immunitysystemic immune inflammation indextotal leukocytes

Identifiers

PMID40145976
PMCPMC13378947

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.