Evidence map›Paper›PMID 40146874›Full record

ArticleJMIR diabetes2025

Applications of AI in Predicting Drug Responses for Type 2 Diabetes.

Shilpa Garg, Robert Kitchen, Ramneek Gupta, Ewan Pearson

Abstract read
In one paragraph

Article in JMIR diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Drug response in the era of precision medicine: A methodological review.Computational and structural biotechnology journal · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shilpa GargDiabetes Endocrinology and Reproductive Biology, School of Medicine, University of Dundee, Ninewells Avenue, Dundee, DD1 9SY, United Kingdom, 44 7443787733.ORCID http://orcid.org/0009-0004-5086-4744
Robert KitchenNovo Nordisk, Oxford, United Kingdom.ORCID http://orcid.org/0000-0003-1443-8559
Ramneek GuptaNovo Nordisk, Oxford, United Kingdom.ORCID http://orcid.org/0000-0001-6841-6676
Ewan PearsonDiabetes Endocrinology and Reproductive Biology, School of Medicine, University of Dundee, Ninewells Avenue, Dundee, DD1 9SY, United Kingdom, 44 7443787733.ORCID http://orcid.org/0000-0001-9237-8585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unlabelled: Type 2 diabetes mellitus has seen a continuous rise in prevalence in recent years, and a similar trend has been observed in the increased availability of glucose-lowering drugs. There is a need to understand the variation in treatment response to these drugs to be able to predict people who will respond well or poorly to a drug. Electronic health records, clinical trials, and observational studies provide a huge amount of data to explore predictors of drug response. The use of artificial intelligence (AI), which includes machine learning and deep learning techniques, has the capacity to improve the prediction of treatment response in patients. AI can assist in the analysis of vast datasets to identify patterns and may provide valuable information on selecting an effective drug. Predicting an individual's response to a drug can aid in treatment selection, optimizing therapy, exploring new therapeutic options, and personalized medicine. This viewpoint highlights the growing evidence supporting the potential of AI-based methods to predict drug response with accuracy. Furthermore, the methods highlight a trend toward using ensemble methods as preferred models in drug response prediction studies.

Indexed as

AIartificial intelligencedeep learningdrug responsemachine learningMLtreatment response predictiontype 2 diabetes

Identifiers

PMID40146874
PMCPMC11967697

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.