Evidence map›Paper›PMID 40147249›Full record

ArticleUltrasonics sonochemistry2025

Evaluation of drying methods and green extraction techniques to enhance the recovery of bioactive compounds from hop leaves: A sustainable approach for the valorisation of agricultural by-products.

Katya Carbone, Valentina Macchioni

Abstract readEvaluation Study
In one paragraph

Article in Ultrasonics sonochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Microbial production of xanthohumol driven by synthetic biology approaches.World journal of microbiology & biotechnology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katya CarboneCREA Research Centre for Olive, Fruit and Citrus Crops, Via di Fioranello 52, 00134 Rome, Italy. Electronic address: katya.carbone@crea.gov.it.
Valentina MacchioniCREA Research Centre for Olive, Fruit and Citrus Crops, Via di Fioranello 52, 00134 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of different drying techniques and green extraction methods on bioactive compounds in hop leaves, typically considered as waste material. Freeze-drying (FD) and oven-drying (OD) were compared for drying the leaves of five hop varieties, while the study focused on the use of microwave (MAE) and ultrasound (UAE) as innovative extraction techniques. The influence of these factors was then evaluated on several bioactive compounds, including polyphenols, flavonoids, pigments, and xanthohumol, as well as the antioxidant capacity and α-glucosidase inhibition of the extracts obtained. MAE yielded higher total polyphenol and flavan content (TPC and FLC, respectively) values than UAE. Similarly, FD samples showed higher TPC and FLC values than OD ones, whereas chlorophyll b was consistently more abundant than chlorophyll a in all samples. HPLC analysis identified catechin, epigallocatechin gallate, and p-hydroxybenzoic acid as the predominant phenolic compounds. Xanthohumol concentrations ranged from 0.04 ± 0.00 to 1.12 ± 0.03 mg g

Indexed as

AgricultureChemical FractionationDesiccationGreen Chemistry TechnologyHumulusPlant LeavesAntioxidantsFlavonoidsGlycoside Hydrolase InhibitorsMicrowavesPlant ExtractsAntioxidantsFlavonoidsGlycoside Hydrolase InhibitorsPlant ExtractsGreen extraction techniquesHop leavesHumulus lupulus LPolyphenolsXanthohumol, drying techniques

Identifiers

PMID40147249
PMCPMC11987633

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.