Evidence mapPaperPMID 40147430Full record

ArticlePublic health genomics2025

Effect of Trust in Science on Parental Reactions to Messaging about Children's Epigenetics-Related Obesity Risk.

Emma M Schopp, Rebecca A Ferrer, Sherine El-Toukhy, Susan Persky

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Article in Public health genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Emma M SchoppNational Human Genome Research Institute, NIH, Bethesda, Maryland, USA.
Rebecca A FerrerNational Cancer Institute, NIH, Rockville, Maryland, USA.
Sherine El-ToukhyNational Institute on Minority Health and Health Disparities, NIH, Bethesda, Maryland, USA.
Susan PerskyNational Human Genome Research Institute, NIH, Bethesda, Maryland, USA.

Funding

Communication of genomic information in clinical, community, and digital contextsZIAHG200383 · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · 2025 to 2025
$94k
Eating and Feeding Behavior: Exploring Phenotypes and Influencing OutcomesZIAHG200396 · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · 2025 to 2025
$94k
Intramural NIH HHS ZIA HG200383Intramural NIH HHS ZIA HG200396NHGRI NIH HHS
6 · The paper itself

Abstract

introductionAccumulating evidence suggests that preconception epigenetic changes elevate the risk for obesity throughout the lifespan. Little is known about how parents may react to learning about parent-child epigenetic transmission of obesity risk. Further, it is unclear how trust in science may moderate these responses.

methodsWe compared risk perceptions, behavioral intentions, perceived control, and information-focused ratings of 322 parents with high weight status who were randomized to read an article about the role of preconception epigenetics in intergenerational obesity risk transmission, versus three comparators that focused on genetics, family environment, or an unrelated topic.

resultsParents had largely similar reactions to the epigenetics, genetics, and family environment articles in terms of perceived credibility, relevance, and threat response, but the epigenetics article failed to produce the elevated cognitive (F(3, 310) = 3.027, p = 0.030) and affective/intuitive (F(3, 310) = 3.05, p = 0.029) risk perceptions observed in response to the genetics and family environment articles compared to control. Science trust moderated individual reactions to the epigenetics concepts, such that those with low science trust exhibited lower attentiveness to the epigenetics article (F(4, 249) = 2.92, p = 0.022), and groups with low, medium, or high science trust exhibited distinct reaction profiles in terms of affective/intuitive risk perception (F(6, 310) = 2.40, p = 0.028).

conclusionAn audience's trust in science should be considered when tailoring messages about the role of epigenetics in conveying obesity risk from parent to child.

Indexed as

Epigenesis, GeneticObesityParentsTrustAdultChildFemaleHumansMalePediatric ObesityEpigeneticsHealth communicationScience trust

Identifiers

PMID40147430
PMCPMC12083241

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.