Evidence map›Paper›PMID 40149274›Full record

ReviewCancers2025

Therapeutic Potential of

Gabriela Mitea, Irina Mihaela Iancu, Verginica Schröder, Adrian Cosmin Roșca, Valeriu Iancu, Ruxandra-Mihaela Crețu, Horațiu Mireșan

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriela MiteaDepartment of Pharmacology, Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania.ORCID 0009-0000-3442-7107
Irina Mihaela IancuDepartment of Toxicology, Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania.ORCID 0009-0004-1589-573X
Verginica SchröderDepartment of Cellular and Molecular Biology, Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania.ORCID 0000-0001-8876-1901
Adrian Cosmin RoșcaDepartment of Analysis and Quality Control of Drugs, Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania.
Valeriu IancuDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania.
Ruxandra-Mihaela CrețuNational Institute of Research and Development for Biological Sciences, "Stejarul" Biological Research Centre, 060031 Bucharest, Romania.
Horațiu MireșanDepartment of Toxicology, Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania.ORCID 0000-0002-7863-7138

Funding

the Core Program within the National Research, Development, and Innovation Plan 2022-2027, carried out with the support of MRID project no. 23020301
6 · The paper itself

Abstract

backgroundGastrointestinal tract cancers represent a significant worldwide health concern, accounting for almost one-third of cancer-related deaths. The existing chemotherapy drugs used in gastrointestinal cancers are ineffective, so prognosis is poor, recurrence and metastasis rates are high, and survival time remains short, necessitating the development of novel antitumor drugs that exhibit low toxicity and less potential for the development of drug resistance. This challenge is considerable, but evidence from the past decades supports the medicinal properties and functionalities of bioactive compounds such as flavonoids and acid phenolics with anticancer activities. Our purpose was to find data on the relationship between gastrointestinal cancer and bioactive compounds from

resultsStudies highlight the potential of bioactive compounds from

conclusionsThe studies reviewed suggest that polyphenols from

Indexed as

antineoplastic agentsapoptosiscolon cancercolorectal cancergastric canceroncologypolyphenolsPrunus

Identifiers

PMID40149274
PMCPMC11940452

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.