Evidence map›Paper›PMID 40149287›Full record

ArticleCancers2025

ASPH Is a Metastatic Factor and Therapeutic Target in Chondrosarcoma.

Xiaojuan Sun, Jesse Hart, Ross Taliano, Janine Molino, Joseph H Schwab, Sjoerd Nota, Katsuya Nagaoka, Songhua Zhang, Mark Olsen, Rolf Carlson and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Exploring adenosine analogs for chondrosarcoma therapy:Molecular therapy. Nucleic acids · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaojuan SunDepartment of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Jesse HartDepartments of Pathology, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.ORCID 0000-0002-4169-2854
Ross TalianoDepartments of Pathology, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Janine MolinoDepartment of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Joseph H SchwabDepartment of Orthopaedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02115, USA.
Sjoerd NotaDepartment of Orthopaedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02115, USA.
Katsuya NagaokaLiver Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.ORCID 0000-0002-7152-6101
Songhua ZhangLiver Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.
Mark OlsenPharmacometrics Center of Excellence, Midwestern University, Downer's Grove, IL 60515, USA.ORCID 0000-0003-2871-1923
Rolf CarlsonLiver Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.
Jack WandsLiver Research Center, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.
Richard M TerekDepartment of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.ORCID 0000-0002-6322-6790

Funding

Pilot Projects ProgramP30GM122732 · NIGMS · RHODE ISLAND HOSPITAL · PI CRISCO, JOSEPH J · 2017 to 2021
$6.6M
ASPH Targeted Therapy for ChondrosarcomaR01CA270795 · NCI · RHODE ISLAND HOSPITAL · PI RICHARD M TEREK · 2023 to 2026
$2.6M
NCI NIH HHS R01 CA270795NIGMS NIH HHS P30 GM122732NIH HHS R01CA270789
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ASPH knockoutbone cancerchondrosarcomametastasisprecision medicinesarcomasmall molecule inhibitortargeted therapy

Identifiers

PMID40149287
PMCPMC11939963

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.