Evidence map›Paper›PMID 40151247›Full record

ArticleJACS Au2025

Redesigned Pathway for

Xin Xin, Dan-Feng Liu, Shi-Chang Liu, Zhi-Hua Liu, Ying-Jin Yuan, Bing-Zhi Li

Abstract read
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Biosynthesis of vanillin glucoside inSynthetic and systems biotechnology · 2027
    Article
  2. Enzyme promiscuity-driven co-production of flavonoid 7-Synthetic and systems biotechnology · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin XinFrontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, China.
Dan-Feng LiuFrontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, China.
Shi-Chang LiuFrontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, China.
Zhi-Hua LiuFrontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, China.
Ying-Jin YuanFrontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, China.ORCID https://orcid.org/0000-0003-0553-0089
Bing-Zhi LiFrontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, China.ORCID https://orcid.org/0000-0003-4121-3048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vanillin, known as the "queen of flavors", is an extensively used and important aromatic compound with multiple functions, including aldehyde, ether, and hydroxyl. Converting lignocellulosic biomass-derived substrates to natural vanillin is sustainable and economical through artificial cell factories. However, the inefficiency of exogenous enzymes and the toxic effect of vanillin on cells limit its production. In this study, pathway reconstruction and integration site optimization of

Identifiers

PMID40151247
PMCPMC11937998

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.