ArticleMagnetic resonance in medicine2025
Quantitative susceptibility mapping of the human carotid artery: Assessing sensitivity to elastin and collagen ex vivo.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Microbial Metabolite 4EPS Inhibits AT1R to Reduce Blood Pressure and Aortic Aneurysm Outcome.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Mapping heterogeneous region- and tissue-specific brain ageing patterns using quantitative MRI.Brain communications · 2026Article
- Quantitative susceptibility mapping of the human carotid artery: Assessing sensitivity to elastin and collagen ex vivo.Magnetic resonance in medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeThe aim is to establish the relationship between carotid susceptibility and microstructural components in diseased carotid arteries.
methodsExcised cadaveric carotid arteries (n = 5) were scanned using high-resolution QSM at 7 Tesla. After ex vivo imaging, all samples were brought to histology and stained for elastin, collagen, cells, and calcium. An image registration pipeline was used in combination with semi-quantitative, regional histology analysis to evaluate relationships between MRI and microstructural components.
resultsWeak, non-significant (p > 0.05) correlations were found between all components and regional magnitude and R
conclusionTissue magnetic susceptibility in diseased human carotid arteries was shown to be significantly correlated with the dominant microstructural components of pathological human cadaver samples-elastin and collagen. Knowing that elastin and collagen are disrupted in vascular disease progression, QSM offers clinically translatable potential for novel disease biomarkers.
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