Evidence map›Paper›PMID 40152945›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Effects of Prothrombin on Podocytopathy and Proteinuria in Glomerular Disease.

Amanda P Waller, Katelyn J Wolfgang, Iva Pruner, Zachary S Stevenson, Eman Abdelghani, Kaushik Muralidharan, Tasha K Wilkie, Angela R Blissett, Edward P Calomeni, Tatyana A Vetter and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Pulmonary branch embolism after shortZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Amanda P WallerCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0003-1522-6021
Katelyn J WolfgangCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Iva PrunerCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0002-8803-5907
Zachary S StevensonCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Eman AbdelghaniCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0002-2308-6527
Kaushik MuralidharanCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0002-3457-5019
Tasha K WilkieCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Angela R BlissettDepartment of Pathology, The Ohio State University College of Medicine, Columbus, Ohio.
Edward P CalomeniDepartment of Pathology, The Ohio State University College of Medicine, Columbus, Ohio.ORCID 0000-0002-6664-0479
Tatyana A VetterDepartment of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio.ORCID 0000-0002-9904-9140
Sergey V BrodskyDepartment of Pathology, The Ohio State University College of Medicine, Columbus, Ohio.ORCID 0000-0003-4570-5883
William E SmoyerCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0003-1982-9938
Marvin T NiemanDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio.ORCID 0000-0003-2602-023
Bryce A KerlinCenter for Clinical and Translational Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0002-1756-8271

Funding

Thrombin-Mediated Podocyte Injury MechanismsR01DK124549 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KERLIN, BRYCE ANDREW · 2021 to 2025
$2.1M
Coagulation Protease Signaling in Glomerular DiseaseK08DK103982 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KERLIN, BRYCE ANDREW · 2015 to 2019
$744k
Investigating the Utility of Nanobodies for Glomerular Disease TreatmentR03DK118315 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KERLIN, BRYCE ANDREW · 2018 to 2019
$228k
NIDDK NIH HHS K08 DK103982NIDDK NIH HHS K08DK103982NIDDK NIH HHS R01 DK124549NIDDK NIH HHS R01DK124549NIDDK NIH HHS R03 DK118315NIDDK NIH HHS R03DK118315
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiovascularglomerular diseasehypoalbuminemiapodocyteproteinuria

Identifiers

PMID40152945
PMCPMC12187242

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.