Evidence map›Paper›PMID 40155996›Full record

ArticleJournal of health, population, and nutrition2025

Breaking barriers: novel reference equations for the six-minute walk distance and work in obese Chinese adults.

He Zou, Xiaoshu Chen, Jia Zhang, Xinlei Wu, Senxiang Wu, Cong Lin, Yuan Zhu, Lianpin Wu

Abstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

He Zou *Department of Cardiology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Xiaoshu Chen *Department of Cardiology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Jia Zhang *Department of Medical Inspection, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Xinlei Wu *Department of Cardiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Senxiang WuDepartment of Neurology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Cong LinDepartment of Cardiology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Yuan ZhuDepartment of Nephrology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Lianpin WuDepartment of Cardiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. 476159415@163.com.

Funding

Science and Technology Plan Project of Wenzhou Municipality Grant No. 2024Y2965
6 · The paper itself

Abstract

backgroundThe six-minute walk test (6MWT) is a key tool for assessing fitness in obese individuals, but existing reference equations for the six-minute walk distance (6MWD) are limited and overlook the six-minute walk work (6MWW), in turn limiting the clinical applicability of the test. This study aims to establish new 6MWD and 6MWW equations to improve our understanding of functional capacity in obese Chinese adults.

methodsA cross-sectional study was conducted at Wenzhou People's Hospital from July 2021 to June 2023. Obese Chinese adults (BMI > 30 kg/m²), aged 18-69 years, completed the 6MWT following the ATS/ERS guidelines. Stepwise multiple regression was used to create sex-specific reference equations for the 6MWD and 6MWW.

resultsA total of 309 obese Chinese adults participated in this study, achieving a mean 6MWD of 550.7 ± 45.85 m and a mean 6MWW of 46149.9 ± 6403.58 kg·m. Sex-specific equations for the 6MWD and 6MWW explained a significant portion of the variance in the values (34-61%).

conclusionThe proposed reference equations for the 6MWD and 6MWW increase the accuracy and applicability of functional capacity assessment tests, outperforming existing reference equations. The inclusion of the 6MWW provides a relatively novel metric that integrates metabolic workload and mechanical efficiency, offering unique insights into the functional performance of obese individuals and allowing tailored health interventions.

Indexed as

East Asian PeopleExercise TestObesityWalkingWalk TestAdolescentAdultAgedChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedReference ValuesYoung AdultFunctional capacityObesityReference equationsSix-minute walking test

Identifiers

PMID40155996
PMCPMC11954308

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.