Evidence map›Paper›PMID 40159185›Full record

ReviewProceedings of the Japan Academy. Series B, Physical and biological sciences2025

Conformational dynamics and molecular interactions of natural products: unveiling functional structures in biological membranes.

Michio Murata, Masayuki Satake, Nobuaki Matsumori

Abstract readReview
In one paragraph

Review in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michio MurataGraduate School of Science, Osaka University.ORCID http://orcid.org/0000-0002-1600-145X
Masayuki SatakeDepartment of Chemistry, School of Science, The University of Tokyo.ORCID http://orcid.org/0000-0001-8508-3551
Nobuaki MatsumoriDepartment of Chemistry, Graduate School of Science, Kyushu University.ORCID http://orcid.org/0000-0003-0495-2044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structural studies of natural products have been a driving force in the development of organic chemistry throughout its long history, especially in the early years. Recently, structure determination based on new concepts has also gained momentum. In this review we will mainly discuss the functional structures of natural products that account for the mechanisms of action largely from our studies. The topics include marine natural products, amphidinols, and ladder-shaped polyether compounds, which are known as potent antifungal agents and important marine biotoxins, respectively. Nuclear magnetic resonance studies for determining the stereochemistry of amphidinol 3 and its conformation in lipid-bilayer membranes will be presented in detail.

Indexed as

Biological ProductsCell MembraneLipid BilayersMolecular ConformationBiological ProductsLipid Bilayersamphidinolbrevisulcatic acidfunctional structurelipid bilayernatural product chemistrysolid-state NMR

Identifiers

PMID40159185
PMCPMC12332416

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.