Evidence map›Paper›PMID 40160570›Full record

ReviewReviews in cardiovascular medicine2025

Risk Factors for Adverse Outcomes in Connective Tissue Disease-Associated Pulmonary Hypertension.

Gayane Matusov, Maryam Shams, Karim Ibrahim, Areg Hovsepyan, Yuri Matusov

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gayane MatusovDepartment of Internal Medicine, Scripps Clinic, La Jolla, CA 92037, USA.ORCID https://orcid.org/0009-0000-7892-4658
Maryam ShamsDepartment of Internal Medicine, Sutter Roseville Medical Center, Roseville, CA 95661, USA.
Karim IbrahimDepartment of Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Areg HovsepyanDepartment of Hospital Medicine, Adventist Health Simi Valley, Simi Valley, CA 93065, USA.ORCID https://orcid.org/0009-0009-0649-9221
Yuri MatusovDepartment of Medicine, Division of Pulmonary & Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID https://orcid.org/0000-0002-6614-2314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a rare, life-threatening condition that can be associated with connective tissue disease (CTD). The incidence and prevalence of PH in CTD varies by disease, whereby certain disease manifestations are particularly associated with PH; nonetheless, once present, PH is almost uniformly a major driver of adverse outcomes. In this paper, the authors review the published literature on major CTDs, including systemic sclerosis and systemic lupus erythematosus, and summarize the risk factors for developing PH in each disease and risk factors for adverse outcomes and mortality among patients with CTD-PH. This review highlights the need for early diagnosis of PH in CTD and the impact of PH overlap syndromes on patient outcomes, providing the practicing clinician with a practical summary of CTD-PH.

Indexed as

autoimmune diseaseconnective tissue diseasepulmonary hypertensionsclerodermasystemic lupus erythematosus

Identifiers

PMID40160570
PMCPMC11951484

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.