ArticlemicroPublication biology2025
The potential impact of lipopolysaccharides (LPS) interactions on light-activated ion channels and pumps.
Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Isoflurane causes muscle contraction inmicroPublication biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optogenetics, the expression of light-activated ion channels and pumps, has the potential in therapeutic treatments for various pathologies. Thus, it is of interest to investigate pharmacological agents, immunological responses, and disease states like bacterial septicemia to learn if light-activated ion channels and pumps are compromised. Bacterial septicemia may impede the function of light-activated channels due to direct actions of lipopolysaccharides. This study explored the effects of activating light-sensitive channels (channelrhodopsin and halorhodopsin) before, during, and after exposure of lipopolysaccharides. Lipopolysaccharide itself did not directly impede the action of LPS but varied because of the effect on ion gradients by changes in membrane potential by lipopolysaccharides.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.