Evidence map›Paper›PMID 40161449›Full record

ArticleInternational journal of general medicine2025

Association of Butyryl Cholinesterase and Recurrent Ischemic Stroke: A Cross-Sectional Study.

Ruomeng Chen, Kun Zhang, Hui Liu, Lijuan Liu, Hui Li, Yan Yan, Zhou Zhou, Chaoyue Meng, Xuelin Wang, Haoran Wu and 3 more

Abstract read
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Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Ruomeng ChenDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Kun ZhangDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Hui LiuDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Lijuan LiuDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Hui LiDepartment of Neurology, Hengshui People's Hospital, Hengshui, Hebei, People's Republic of China.
Yan YanDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Zhou ZhouDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Chaoyue MengDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Xuelin WangDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Haoran WuDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Ruihan MiaoDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Rui WangDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Xiaoyun LiuDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.ORCID 0009-0003-8604-904X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Exploring novel relevant factors associated with recurrent ischemic stroke. Methods: This is a retrospective study, patients were divided into first-ever ischemic stroke group and recurrent ischemic stroke groups. We conducted a comparative analysis of baseline data between the two groups. Multifactorial logistic regression analysis was performed to identify factors associated with recurrent ischemic stroke. Grouped according to butyryl cholinesterase levels, to elucidate the relationship between butyryl cholinesterase levels and stroke recurrence. Results: A total of 2029 patients were included, with 1174 in the first-ever ischemic stroke group and 855 in the recurrent ischemic stroke group. Age, hypertension, diabetes, alanine aminotransferase, and lipoprotein(a) were identified as risk factors for recurrent ischemic stroke (ALL Conclusion: Age, hypertension, diabetes, alanine aminotransferase, and lipoprotein(a) are independent risk factors for the recurrence of ischemic stroke. The inverse association between butyryl cholinesterase levels and stroke recurrence suggests butyryl cholinesterase may serve as a potential target for therapeutic intervention to improve the prognosis of ischemic stroke.

Indexed as

butyryl cholinesterasecerebral infarctioncross-sectional studyLipoprotein arecurrent ischemic stroke

Identifiers

PMID40161449
PMCPMC11955186

What Socratic holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.