ArticleClinical parkinsonism & related disorders2025
Efficacy of virtual reality-based cognitive behavioral group therapy in enhancing emotional well-being and quality of life in Parkinson's disease: A randomized controlled trial.
Article in Clinical parkinsonism & related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Trial
- Exploring the therapeutic potential of Astragalin in Parkinson's disease: a network pharmacology approach.Annals of medicine and surgery (2012) · 2026Article
- Perioperative mental health needs in urological and genitourinary surgery: a scoping review.Frontiers in public health · 2026Article
- Factors Associated With Improved Physical Performance in Individuals With Parkinson's Disease Using the Fisior® Sequential Square Mat Walking Training Program: A Secondary Gender-Stratified Analysis of a Randomized Controlled Trial.Journal of central nervous system disease · 2026Article
- The role of artistic creativity in predicting difficulties in emotion regulation and reducing social anxiety: insights from a cross-sectional analysis.Annals of medicine and surgery (2012) · 2026Article
- Exposure-Based Intervention in Virtual Reality to Address Kinesiophobia in Parkinson's Disease: A Narrative Review.Journal of clinical medicine · 2025Review
- Psychological self-efficacy and coping styles as mediators between perceived stress and IBS symptom severity: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- Exploring the Effectiveness of Immersive Virtual Reality Rehabilitation for Parkinson's Disease: A Narrative Review.Journal of clinical medicine · 2025Review
- Mechanisms of Virtual Reality-Based Relaxation in Older Adults: A Scoping Review.Journal of clinical medicine · 2025Review
- Efficacy of foot reflexology in reducing migraine pain: a randomized controlled trial.Annals of medicine and surgery (2012) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study evaluates the effectiveness of virtual reality-based cognitive behavioral group therapy (VR-CBGT) in improving emotional well-being and quality of life in individuals with Parkinson's disease. Methods: A randomized controlled trial was conducted in 2023 at Roozbeh Hospital, Tehran, with 90 Parkinson's patients. Participants were randomly assigned to an intervention group receiving 12 VR-CBGT sessions over three months with a control group receiving standard medical care without psychological intervention. Emotional well-being was assessed using the Hospital Anxiety and Depression Scale (HADS), and quality of life was measured with the Parkinson's Disease Questionnaire-39 (PDQ-39) before and after the intervention. Data were analyzed using Multivariate Analysis of Covariance (MANCOVA) in SPSS-25. Results: The intervention group demonstrated a significant improvement in emotional well-being (HADS-total score reduction of 7.2 points, P < 0.001) and quality of life (PDQ-39 total score improvement of 12.5 %, P = 0.002) compared to the control group. VR-CBGT explained 18 % of the variance in emotional well-being and 26 % in quality of life. Conclusion: These findings highlight VR-CBGT as an effective complementary intervention for enhancing psychological health and overall quality of life in Parkinson's patients. The immersive nature of VR fosters engagement and facilitates cognitive and emotional processing, supporting its integration into multidisciplinary treatment approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.