Evidence map›Paper›PMID 40161697›Full record

ArticlebioRxiv : the preprint server for biology2025

Binding affinities for 2D protein dimerization benefit from enthalpic stabilization.

Adip Jhaveri, Smriti Chhibber, Nandan Kulkarni, Margaret E Johnson

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Adip JhaveriTC Jenkins Department of Biophysics, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218.
Smriti ChhibberTC Jenkins Department of Biophysics, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218.
Nandan KulkarniTC Jenkins Department of Biophysics, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218.
Margaret E JohnsonTC Jenkins Department of Biophysics, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218.ORCID 0000-0001-9881-291X

Funding

Mechanisms of Protein Self-Assembly Coupled to Membrane Mechanics in the Cell.R35GM133644 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI JOHNSON, MARGARET ELLEN · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM133644
6 · The paper itself

Abstract

Dimerization underpins all macromolecular assembly processes both on and off the membrane. While the strength of dimerization,

Identifiers

PMID40161697
PMCPMC11952360

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.