ArticleIndian journal of anaesthesia2025
Comparison between opioid-based anaesthesia technique and opioid-free anaesthesia technique in patients undergoing laparotomy for gynaecological malignancy: A randomised controlled trial.
Article in Indian journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07787858 (Effect of Opioid-Free Versus Opioid-Based Anesthesia on Postoperative Analgesia in Patients Undergoing Discectomy Surgery), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Opioid-Free Versus Opioid-Based Anesthesia on Postoperative Analgesia in Patients Undergoing Discectomy Surgery
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of opioid-free anesthetic on postoperative complication following gynecological surgery: a meta-analysis.Revista da Escola de Enfermagem da U S P · 2025Pooled it
- Anaesthesia at the edge: Thyroid stimulating hormone >100 µIU/mL in time-sensitive surgery.Indian journal of anaesthesia · 2026Article
- Indian Journal of Anaesthesia Infographics of published articles.Indian journal of anaesthesia · 2025Article
- Opioid-Free Anesthesia Versus Opioid-Balanced Anesthesia in Breast Surgeries: A Randomized Study.Cureus · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: To investigate whether opioid-free anaesthesia (OFA) or opioid-based anaesthesia (OBA) technique with ultrasound (US)-guided rectus sheath block (RSB) provides early recovery and less opioid-related side effects in patients undergoing laparotomy for gynaecological malignancy. Methods: This was a double-blind randomised controlled trial. Fifty female patients of the American Society of Anesthesiologists (ASA) physical status I-II, aged 18-65 years, and scheduled to undergo elective gynaecological laparotomy under general anaesthesia were included. The patients were randomised into two groups. Both received US-guided RSB with 10 mL of local anaesthetic on each side. Group OBA ( Results: The time to attain PACU discharge criteria was comparable between the groups; however, the time to extubation and time to shift to the PACU was higher in Group OFA ( Conclusion: OFA provides comparable postoperative analgesia and time to attain PACU discharge in adult patients undergoing open gynaecological oncological surgery under general anaesthesia.
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Registered trials
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