Evidence mapPaperPMID 40162007Full record

ArticleAJOG global reports2025

Effect of different combinations of serum antimüllerian hormone levels and body mass index on pregnancy outcomes in women with polycystic ovary syndrome.

Yue Niu, Xinwei Han, Huiying Xiao, Ruolan Miao, Gege Ouyang, Qian Wang, Daimin Wei

Abstract read
In one paragraph

Article in AJOG global reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yue NiuState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).
Xinwei HanState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).
Huiying XiaoState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).
Ruolan MiaoState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).
Gege OuyangState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).
Qian WangState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).
Daimin WeiState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China (Niu, Han, Xiao, Miao, Ouyang, and Wei).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth antimüllerian hormone and body mass index are associated with the pregnancy outcomes in women with polycystic ovary syndrome undergoing in vitro fertilization.

objectiveThis study aimed to explore the effect of different combinations of antimüllerian hormone and body mass index on pregnancy outcomes in women with polycystic ovary syndrome undergoing in vitro fertilization. STUDY

designThis was a post hoc secondary analysis of a multicenter randomized trial. A total of 625 women from 1 center with antimüllerian hormone levels measured before in vitro fertilization treatment were classified into 6 groups: group A (normal weight and low antimüllerian hormone group), group B (normal weight and intermediate antimüllerian hormone group), group C (normal weight and high antimüllerian hormone group), group D (overweight/obese and low antimüllerian hormone group), group E (overweight/obese and intermediate antimüllerian hormone group), and group F (overweight/obese and high antimüllerian hormone group).

resultsAfter adjustment via multivariate logistic regression, the overweight/obese and high antimüllerian hormone group (group F) had a higher risk of clinical pregnancy miscarriage (adjusted odds ratio, 3.30; 95% confidence interval, 1.35-8.07) than the normal weight and intermediate antimüllerian hormone group (group B). Both the normal weight and high antimüllerian hormone group (group C; adjusted odds ratio, 3.74; 95% confidence interval, 1.06-13.24) and the overweight/obese and high antimüllerian hormone group (group F; adjusted odds ratio, 3.61; 95% confidence interval, 1.05-12.38) had higher risks of ovarian hyperstimulation syndrome than the normal weight and intermediate antimüllerian hormone group (group B).

conclusionIn women with polycystic ovary syndrome, high serum antimüllerian hormone levels were associated with an increased risk of clinical pregnancy miscarriage in women who were overweight/obese but not in those with normal weight.

Indexed as

antimüllerian hormonebody mass indexclinical pregnancy miscarriageovarian hyperstimulation syndromepolycystic ovary syndrome

Identifiers

PMID40162007
PMCPMC11952798

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.