In one paragraphArticle in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
15 authors.
Margo B HestonWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0002-0980-2275 Jordan P TeagueWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0001-6688-6949 Karly A CodyDepartment of Neurology and Neurological Sciences, Stanford University Center for Academic Medicine, 453 Quarry Road, Palo Alto, CA 94304.ORCID 0000-0001-5996-2560 Yuetiva DemingWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0001-7512-5703 Elena Ruiz de ChavezWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.
Jacob MorseWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0009-0004-1007-2531 Nathaniel A ChinWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0001-8008-9356 Corinne D EngelmanWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0003-4750-5607 Richard J ChappellWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.
Rebecca E LanghoughWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0003-0025-744X Carey E GleasonWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0001-6210-4671 Lindsay R ClarkWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0003-4837-7627 Megan L ZuelsdorffWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0002-9632-475X Tobey J BetthauserWisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC 2420, Madison, WI 53792-2420.ORCID 0000-0001-8856-1352 Alzheimer’s Disease Neuroimaging Initiative
Funding
Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0MWisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Barbara Brigitta Bendlin · 2019 to 2026
$34.5MAfrican Americans Fighting Alzheimer’s in Midlife (AA-FAIM)R01AG054059 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAREY E GLEASON · 2016 to 2026
$15.3MMulti-cohort study of factors that influence Alzheimer's disease biomarker and dementia timingR01AG080766 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI TOBEY JAMES BETTHAUSER · 2023 to 2026
$3.1MNIA NIH HHS P30 AG062715NIA NIH HHS R01 AG054059NIA NIH HHS R01 AG080766NIA NIH HHS U01 AG024904
6 · The paper itselfAbstract
introductionElevated tau is temporally proximal to dementia onset but less is known about factors influencing T+ onset age and time to dementia following T+ in Alzheimer's disease. We used sampled iterative localized approximation (SILA) estimated T+ onset age (ETOA) to investigate factors associated with T+ age and time from T+ to dementia onset in ADNI.
methodsUsing SILA-estimated A+ and T+ onset ages derived from
resultsHigher amyloid, DISCUSSION: This work highlights the prognostic value of ETOA and the need to better characterize factors contributing to ETOA and dementia onset in AD.
Indexed as
Alzheimer’s diseaseamyloid betaAPOEdementia riskestimated tau onset ageliteracy exposureSILAsocial determinants of healthtemporal modeling
Identifiers
PMID40162285
PMCPMC11952611
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
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