Evidence map›Paper›PMID 40164739›Full record

ArticleScientific reports2025

Analysis on the causes of unsatisfactory prevention effect of postpartum VTE in Chinese women.

Yonghui Xu, Fei Xiao, Ji He, XingSheng Xue, Yangting Li, Sha Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Risk Stratification and Safety Profile of Pharmacological Prophylaxis for Venous Thromboembolism in Postpartum Women Following Cesarean Section: A Comparative Evaluation.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yonghui XuDepartment of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, China.
Fei XiaoDepartment of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, China.
Ji HeDepartment of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, China.
XingSheng XueDepartment of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, China.
Yangting LiDepartment of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, China.
Sha ZhuDepartment of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, China. zhusha_hxey@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preventing venous thromboembolism (VTE) in obstetrics remains challenging, with cases still occurring despite preventive measures. The aim of this study is to investigate the underlying causes by analyzing potential issues in current postpartum VTE prevention strategies in China. This retrospective study was conducted in our hospital from May 2021 to August 2024. VTE risk was assessed using the Chinese Expert Consensus on VTE Prevention and Treatment during Pregnancy and Puerperium (Chinese Consensus), and preventive measures were implemented accordingly. Clinical variables, timing of prophylaxis, and the predictive accuracy of the Chinese Consensus were analyzed. The VTE group had higher D-dimer levels and longer hospital stays and shorter gestational ages (P < 0.05). Significant differences were observed in postpartum hemorrhage (PPH), premature birth, autoimmune diseases, and cesarean delivery (P < 0.05). Despite 65.4% receiving thromboprophylaxis, 25.2% developed VTE, with higher incidences in those without prophylaxis. Pneumatic therapy and LMWH were effective in high-risk patients (P < 0.05). Early VTE occurred 6 h postpartum, with 41.8% within 48 h. Most preventive measures were initiated at 24-48 h postpartum, potentially delaying optimal protection. The ROC analysis showed an AUC of 0.497 (P = 0.937), indicating limited predictive efficacy of the Chinese Consensus. Current postpartum VTE prevention is inadequate, as some at-risk patients still miss the opportunity for pneumatic therapy and LMWH anticoagulation after delivery. Initiating LMWH prophylaxis 24 h postpartum appears to be delayed. The predictive ability of the Chinese Consensus for assessing VTE risk is limited. Future research is essential to optimize prevention strategies and reduce the incidence of postpartum VTE.

Indexed as

Postpartum PeriodVenous ThromboembolismAdultAnticoagulantsChinaEast Asian PeopleFemaleFibrin Fibrinogen Degradation ProductsHeparin, Low-Molecular-WeightHumansPregnancyRetrospective StudiesRisk FactorsAnticoagulantsFibrin Fibrinogen Degradation Productsfibrin fragment DHeparin, Low-Molecular-WeightChinese consensusLow molecular weight heparinPostpartumThromboprophylaxisVenous thromboembolism

Identifiers

PMID40164739
PMCPMC11958802

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.