Evidence map›Paper›PMID 40164895›Full record

ReviewAesthetic plastic surgery2025

Essential Pharmaceutical Drugs in the Filler Emergency Kit.

Javier Madero-Pérez, Marta Gil-Martinez, Cristina Muñoz-Gonzalez, Paula Martin-Marfil, Nabil Fakih-Gomez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Javier Madero-PérezJaume I University, Castellón de la Plana, Spain.
Marta Gil-MartinezPrivate Practice, Castellon, Spain.
Cristina Muñoz-GonzalezDepartment of Facial Plastic and Cranio-Maxillo-Facial Surgery, Fakih Hospital, Khaizaran Main Street, Sidon, 00000, Lebanon.
Paula Martin-MarfilDepartment of Endocrinology and Medical Nutrition, Salamanca, Spain.
Nabil Fakih-GomezDepartment of Facial Plastic and Cranio-Maxillo-Facial Surgery, Fakih Hospital, Khaizaran Main Street, Sidon, 00000, Lebanon. info@drnabilfakih.com.ORCID 0000-0003-4464-8258

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe rise in clinical procedures utilizing dermal fillers necessitates preparedness for potential emergencies. Effective management of complications arising from filler use, including vascular occlusions and allergic reactions, hinges on the availability of the appropriate pharmacological supplies.

methodsA two-tiered search in PubMed and Google Scholar was conducted to identify essential drugs for dermal filler emergencies. An initial 10-year review used keywords "Dermal Fillers," "vascular occlusion," and "hyaluronidase," followed by a targeted search on "Resuscitation guidelines," "anaphylaxis management," "allergy fillers," and "lidocaine." This article outlines the critical drug inventory for emergency kits to manage filler-related complications effectively.

resultsAn ORA classification system (Obligatory, Recommended, Advisable) is introduced to categorize essential drugs according to urgency and clinical necessity. The required drugs are grouped based on their application in cases of vascular occlusion without ocular involvement, vascular occlusion with ocular involvement, anaphylactic reactions, cardiopulmonary resuscitation and hemodynamic disorders, delayed reactions, and aseptic, oxygen, and topical treatments. Additionally, the importance of meticulous drug inventory management-including tracking of stock entry, exit, and expiration dates-is emphasized to reduce the risk of shortages.

conclusionEnsuring that filler emergency kit is well stocked with vital pharmacological supplies is imperative for effective emergency management during filler procedures. Adopting systematic inventory practices and utilizing the ORA classification can enhance preparedness and patient safety. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Cosmetic TechniquesDermal FillersHumansDermal FillersAllergic reactionsDermal fillersDrug inventory managementHyaluronidaseORA classificationUFEKVascular occlusion

Identifiers

PMID40164895

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.