Evidence mapPaperPMID 40165263Full record

ArticleDiabetology & metabolic syndrome2025

The effect of beinaglutide as an glucagon-like peptide-1 receptor agonists on cardiometabolic factors: a systematic review and meta-analysis.

Yan Xu, Periyannan Velu, Li Hu, Nathalia Sernizon Guimarães

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Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yan XuDepartment of Emergency Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 64600, China.
Periyannan VeluDepartment of Biochemistry and Biotechnology, Annamalai University, Chidambaram, Tamil Nadu, 608002, India.
Li HuDepartment of Emergency Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 64600, China. huli114@swmu.edu.cn.
Nathalia Sernizon GuimarãesDepartment of Nutrition, School of Nursing, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConsidering the important role of cardiometabolic risk factors in different societies on increasing the burden of non-communicable diseases, in this study we will investigate the possible effects of Beinaglutide as an glucagon-like peptide-1 receptor agonists (GLP-1RAs) on these risk factors.

methodsIn order to identify all randomized controlled trials that investigated the effects of Beinaglutide on cardiometabolic factors, a systematic search was conducted in the original databases using predefined keywords until July 2024. The pooled weighted mean difference and 95% confidence intervals were computed using the random-effects model.

resultsA quantitative meta-analysis results from 7 studies with 872 participants showed that Beinaglutide has a significant lowering effect on weight (WMD: -3.74 kg; 95% CI: -5.03, -2.45), body mass index (BMI) (WMD:-1.64 kg/m

conclusionsThe results of this meta-analysis show that Beinaglutide is effective in reducing factors related to obesity, TG as wll as SBP, especially with longer interventions and lower doses.

Indexed as

BeinaglutideCardiometabolicGLP-1 agonistMeta-analysisObesity

Identifiers

PMID40165263
PMCPMC11959866

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.