Evidence map›Paper›PMID 40165590›Full record

ArticlePhysiological reports2025

Effects of Rho inhibitors on membrane depolarization-induced contraction of male rat caudal arterial smooth muscle.

Kazuki Aida, Reiko Ishii-Nozawa, Mitsuo Mita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kazuki AidaDepartment of Pharmacology, Meiji Pharmaceutical University, Tokyo, Japan.ORCID https://orcid.org/0009-0007-0559-7511
Reiko Ishii-NozawaDepartment of Pharmacology, Meiji Pharmaceutical University, Tokyo, Japan.
Mitsuo MitaDepartment of Cardiovascular Pharmacology, Education and Research Unit for Comprehensive Clinical Pharmacy, Meiji Pharmaceutical University, Tokyo, Japan.

Funding

This work was supported by Grant-in-Aid for Scientific Research granted by the Japan Society for the Promotion of Science (JSPS) KAKENHI JP19K07108
6 · The paper itself

Abstract

We previously reported that depolarization of the vascular smooth muscle plasma membrane activates the Ca

Indexed as

Membrane PotentialsMuscle ContractionMuscle, Smooth, VascularrhoA GTP-Binding ProteinAnimalsArteriesFocal Adhesion Kinase 2Guanine Nucleotide Exchange FactorsMaleMyosin-Light-Chain PhosphatasePhosphorylationProtein Phosphatase 1RatsRats, Sprague-Dawleyrho GTP-Binding ProteinsFocal Adhesion Kinase 2Guanine Nucleotide Exchange FactorsMyosin-Light-Chain PhosphatasePpp1r12a protein, ratProtein Phosphatase 1rhoA GTP-Binding ProteinRhoA protein, ratrho GTP-Binding Proteinsproline‐rich tyrosine kinase 2RhoARho guanine nucleotide exchange factorRhosinY16

Identifiers

PMID40165590
PMCPMC11959149

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.