ArticleActa diabetologica2025
Triglyceride-glucose index is a significant predictor of hospital mortality in non-diabetic critically ill patients with ischemic stroke: a retrospective cohort study of the MIMIC-IV database.
Article in Acta diabetologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Association Between Triglyceride-Glucose Index and in-Hospital Intensive Care Unit Readmission in Ischemic Stroke Patients: A Retrospective Analysis Based on the MIMIC-IV Database.The Kaohsiung journal of medical sciences · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
BACKGROUND AND
aimsThe relationship between the TyG index and outcomes in non-diabetic patients with ischemic stroke admitted to intensive care unit (ICU) has not been validated. This study aims to investigate the correlation between the TyG index and mortality in non-diabetic ICU patients with ischemic stroke.
methodsWe collected data from ICU patients (≥ 18 years) with ischemic stroke and no diabetes. The primary outcome was hospital mortality, and the secondary outcomes were 30-day mortality following admission, hospital length of stay (LOS) and ICU LOS. Cox proportional hazards models and generalized linear models were employed to evaluate association between the TyG index and mortality and LOS, respectively. Nonlinear associations between the TyG index and outcomes were assessed using restricted cubic spline regression models.
resultsA total of 1122 eligible patients were included in this study. The hospital mortality was 10.61%, and 30-day mortality was 16.93%. Multivariate Cox proportional hazards models and generalized linear models revealed the higher of TyG was significantly associated with increased hospital mortality [adjusted HR (95% CI) 1.22 (1.02-1.46), P = 0.0264], 30-day mortality [adjusted HR (95% CI) 1.26 (1.10-1.44), P = 0.0011] and prolonged hospital LOS [adjusted difference (95% CI) 0.52 (0.06-0.97), P = 0.0276].
conclusionsTyG index is a significant predictor of hospital mortality, 30-day mortality, and LOS in non-diabetic ICU patients with ischemic stroke, which could aid clinical decision-making in managing ischemic stroke.
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