Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Proceedings of the National Academy of Sciences of the United States of America · 2025
Article
4 · The record
Corrections and comments
Update of
2024
5 · Who and what money
Authors and funding
5 authors.
Brent Eastman *Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.ORCID 0000-0003-4757-1209
Nobuko Tabuchi *Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.
Xinrui L ZhangDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.
William C SpencerDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.ORCID 0000-0002-9700-8011
Evan S DenerisDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.ORCID 0000-0003-4211-9934
Funding
Gene regulatory mechanisms controlling development of serotonin neuron subtypesR01MH125918 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI DENERIS, EVAN S · 2021 to 2025
$2.9M
Brain serotonin neuron gene regulatory networks and chromatin architectureR01MH117643 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI DENERIS, EVAN S · 2019 to 2024
$2.2M
Intrinsic transcriptional programs for regeneration of serotonergicconnectivityK01NS135573 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI Nobuko Tabuchi · 2024 to 2026
$365k
HHS | NIH | National Institute of Mental Health (NIMH) R01MH117643HHS | NIH | National Institute of Mental Health (NIMH) R01MH125918HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) K01NS135573MEXT | Japan Society for the Promotion of Science (JSPS) NANIMH NIH HHS R01 MH117643NIMH NIH HHS R01 MH125918NINDS NIH HHS K01 NS135573Uehara Memorial Foundation (UMF) 201940009
6 · The paper itself
Abstract
Pathogenic coding mutations are prevalent in human neuronal transcription factors (TFs) but how they disrupt development is poorly understood. Lmx1b is a master transcriptional regulator of postmitotic
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.