ArticleDiscover oncology2025
A two-decade bibliometric analysis of drug resistance in oral cancer research: patterns, trends, and future directions.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundDrug resistance in oral cancer presents a significant challenge in clinical treatment. Understanding the research landscape through bibliometric analysis can provide valuable insights into the development and trends in this field.
objectiveTo comprehensively analyze the global research trends, collaboration patterns, and emerging topics in oral cancer drug resistance research from 2000 to 2024 using bibliometric methods.
methodsPublications related to oral cancer drug resistance were retrieved from the Web of Science core collection database. CiteSpace and VOSviewer were employed to analyze publication trends, research collaboration networks, and keyword co-occurrence patterns. The analysis included annual publication outputs, country contributions, institutional productivity, author collaborations, journal distributions, and research hotspots.
resultsA total of 971 publications were identified, showing a significant increase in research output over the study period, particularly after 2014. China led in publication output (485 articles), followed by Japan (130 articles) and the United States (118 articles). China Medical University was the most productive institution (50 publications). The International Journal of Molecular Sciences, Cancers, and Oral Oncology were the primary publishing venues. Keyword analysis revealed an evolution from basic drug resistance mechanisms to emerging research areas including cancer stem cells, tumor microenvironment, and extracellular vesicles.
conclusionsThis bibliometric analysis demonstrates the rapid growth and evolving nature of oral cancer drug resistance research. The findings highlight the shift towards more sophisticated research areas and strong international collaboration patterns. These insights can guide future research directions and collaboration opportunities in this field.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.