Evidence mapPaperPMID 40169766Full record

Observational studyScientific reports2025

Association between mild renal insufficiency, inflammatory status on initial admission, and 1-year mortality following ST-segment elevation myocardial infarction.

Da Luo, Xiaoying Wang, Liyue Wang, Zheng Hu, Bofang Zhang, Changwu Xu, Hong Jiang, Jing Chen

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04996901 (The Chinese ST-Segment Elevation Myocardial Infarction Primary Percutaneous Coronary Intervention Registry), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04996901 completednot on this map

The Chinese ST-Segment Elevation Myocardial Infarction Primary Percutaneous Coronary Intervention Registry

TypeobservationalSponsorRenmin Hospital of Wuhan UniversityRan2021 to 2021Enrolled5,594ConditionsST-segment Elevation Myocardial Infarction (STEMI)Armsno intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Da Luo *Department of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, 430060, People's Republic of China.
Xiaoying Wang *Department of Cardiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Liyue Wang *Department of Cardiology, Wuhan University of Science and Technology Affiliated Wuchang Hospital, Wuhan, People's Republic of China.
Zheng HuDepartment of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, 430060, People's Republic of China.
Bofang ZhangDepartment of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, 430060, People's Republic of China.
Changwu XuDepartment of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, 430060, People's Republic of China.
Hong JiangDepartment of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, 430060, People's Republic of China.
Jing ChenDepartment of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, 430060, People's Republic of China. chenjing1982@whu.edu.cn.

Funding

Chinese Society of Cardiology's Foundation CSCF2021A02
6 · The paper itself

Abstract

The systemic inflammation tends to increase progressively as kidney function deteriorates. However, it remains unknown whether mild renal insufficiency affects inflammatory response at admission and subsequent clinical outcomes following ST-segment elevation myocardial infarction (STEMI). This study aimed to evaluate the joint, interactive, and mediating effects of estimated glomerular filtration rate (eGFR) and neutrophil-lymphocyte ratio (NLR) at admission on 1-year mortality in STEMI patients. Data were collected from 5,594 consecutive STEMI patients at seven centers (NCT04996901). Mildly reduced eGFR (60-89 mL/min/1.73m

Indexed as

InflammationRenal InsufficiencyST Elevation Myocardial InfarctionAgedFemaleGlomerular Filtration RateHumansLymphocytesMaleMiddle AgedNeutrophilsPrognosisRisk FactorsInflammationMortalityPrognosisRenal insufficiencySTEMI

Identifiers

PMID40169766
PMCPMC11962060

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.