ArticleThe EMBO journal2025
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses.
Abstract read
In one paragraph
Article in The EMBO journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Highlights of 2025: advances in germinal centers.Immunology and cell biology · 2026Review
- Follicular T cells in the ovarian cancer immune microenvironment: biological insights and translational implications.Frontiers in immunology · 2026Review
- Lpar5 regulates the CD8 T-cell response to persistent virus infection by altering exhaustion programming, survival, and NK receptor expression.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
Corrections and comments
- Update of
Authors and funding
26 authors.
Eleonora Sala *School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Maria Nelli *School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0009-0004-5006-0201
Chiara LauraSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Pietro Di LuciaSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Cristian Gabriel BeccariaDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID http://orcid.org/0000-0001-9682-4415
Elisa B BonoDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marta MangioneSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Davide MarottaSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Valentina SpertoSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0009-0009-3160-824X
Marta GrilloSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0000-0001-9064-2274
Leonardo GiustiniDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Fabio TosiSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0009-0005-4509-0227
Jia NieLaboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Daehong KimInstitute of Experimental Immunology, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-1253-8946
Giuliana FuriatoSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Chiara MalpighiDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Eleonora ConsoloSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Burkhard BecherInstitute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Eyal DavidDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Merav CohenDepartment of Clinical Microbiology and Immunology, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Amir GiladiDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Ido AmitDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Remy BosselutLaboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Luca G GuidottiSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0000-0002-0205-2678
Matteo Iannacone *School of Medicine, Vita-Salute San Raffaele University, Milan, Italy. iannacone.matteo@hsr.it.ORCID http://orcid.org/0000-0002-9370-2671
Mirela Kuka *School of Medicine, Vita-Salute San Raffaele University, Milan, Italy. kuka.mirela@hsr.it.ORCID http://orcid.org/0000-0001-9418-1559
Funding
Asher Biotherapeutics Sponsored Research AgreementsEC | European Research Council (ERC) Consolidator Grant 725038EC | European Research Council (ERC) Proof of Concept Grant 957502Fondazione Prossimo Mio FellowshipFondazione SAME DonationGilead Sciences (Gilead) Sponsored Research AgreementsItalian Association for Cancer Research (AIRC) 19891Italian Association for Cancer Research (AIRC) 22737Italy Ministry of Health | Agenzia Italiana del Farmaco, Ministero della Salute (AIFA) GR-2021-12372615Italy Ministry of Health | Agenzia Italiana del Farmaco, Ministero della Salute (AIFA) RF-2018-12365801Ministero dell'Istruzione, dell'Università e della Ricerca (MIUR) PE00000007,INF-ACTMinistero dell'Istruzione, dell'Università e della Ricerca (MIUR) PRIN-2017ZXT5WRMinistero dell'Istruzione, dell'Università e della Ricerca (MIUR) SIR-RBSI14BAO5Ministero dell'Università e della Ricerca (MUR) PRIN-20209Y5YFZMinistero dell'Università e della Ricerca (MUR) PRIN-20224NMLXKMinistero dell'Università e della Ricerca (MUR) PRIN-P2022YKH9RMinistero dell'Università e della Ricerca (MUR) PRIN-P2022Z8HNCVir Biotechnology (Vir) Sponsored Research Agreements
Abstract
CD4
Indexed as
Antibody FormationCell DifferentiationInterferon-gammaT Follicular Helper CellsT-Lymphocytes, Helper-InducerAnimalsDendritic CellsGranzymesHepatocyte Nuclear Factor 1-alphaImmunity, HumoralLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, Inbred C57BLT-Box Domain ProteinsTh1 CellsGranzymesGzmb protein, mouseHepatocyte Nuclear Factor 1-alphaHnf1a protein, mouseInterferon-gammaT-Box Domain ProteinsB-cell ResponsesCD4+ T CellsIFN-γViral Infection
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.