SynthesisBMC public health2025
Association of physical activity, sedentary behaviour, sleep and myopia in children and adolescents: a systematic review and dose-response meta-analysis.
Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of exercise on myopia in children and adolescents and its modifying factors: a systematic review and meta-analysis.BMC pediatrics · 2026Pooled it
- Beyond Screen Time: A Measurement Framework for Behavioral Exposures in Childhood Myopia.Life (Basel, Switzerland) · 2026Review
- Independent and joint associations of out-of-school time moderate-to-vigorous physical activity and sedentary behavior with the risk of central obesity in children and adolescents.Archives of public health = Archives belges de sante publique · 2026Article
- Cross-sectional associations of nighttime sleep and daytime nap duration with myopia in preschool children: the mediating role of body mass index.Frontiers in medicine · 2026Article
- Lifestyle and environmental risk factors for myopia in children: Evidence from a large-scale cross-sectional study in Shandong, China.PloS one · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to systematically evaluate the dose-response relationships between physical activity (PA), sedentary behavior(SB) (including near work [NW] and screen time [ST]), sleep duration (SD), and myopia risk among children and adolescents.
designSystematic review and dose-response meta-analysis.
methodsWe systematically searched PubMed, EMBASE, Cochrane Library, and Web of Science up to November 19, 2024. Methodological quality was assessed using Joanna Briggs Institute (JBI) and ROBINS-I tools. Random-effects meta-analyses were used to estimate categorical and continuous dose-response relationships. Subgroup analyses and sensitivity analyses were performed to explore heterogeneity sources and test robustness.
resultsA total of 45 observational studies (766,848 participants aged 5-19 years) were included. Categorical analyses showed that, compared with the lowest exposure categories, higher PA levels (highest: OR = 0.77, 95% CI: 0.63-0.96; intermediate: OR = 0.76, 95% CI: 0.63-0.93) and longer SD (highest: OR = 0.67, 95% CI: 0.48-0.92; intermediate: OR = 0.82, 95% CI: 0.73-0.92) significantly reduced myopia risk. Conversely, higher levels of NW (highest: OR = 1.71, 95% CI: 1.28-2.27; intermediate: OR = 1.34, 95% CI: 1.19-1.50) and ST (highest: OR = 1.59, 95% CI: 1.14-2.22; intermediate: OR = 1.29, 95% CI: 1.12-1.49) were associated with significantly increased risk. In the continuous dose-response meta-analysis, a linear association was observed between PA, ST, and myopia. Each additional hour of PA per day reduced the risk of myopia by 12%, while each additional hour of ST increased the risk by 31%. Nonlinear associations were found between NW, SD, and myopia. Among children and adolescents, 1.5 and 2.5 h/day of NW increased the risk of myopia by 25% and 29%, respectively. Although longer SD was associated with a reduced risk of myopia, this effect did not reach statistical significance at any exposure level.Subgroup analyses revealed that protective effects of PA were more evident in low- and middle-income countries, smaller sample sizes, and cross-sectional studies, while increased risks related to ST and NW were stronger in low-income settings. No subgroup significantly modified the association between SD and myopia risk.
conclusionIncreasing PA, while limiting ST and NW, effectively reduces the risk of myopia among children and adolescents. The association between sleep duration and myopia remains inconclusive, warranting further investigation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.