Evidence map›Paper›PMID 40170438›Full record

ArticleJournal of applied clinical medical physics2025

BreastWatch: A Varian Eclipse script tool for Community-Based automatic evaluation of breast treatment plans.

Stefano Agostinelli, Daniele Zefiro, Stefania Garelli, Francesca Cavagnetto, Marco Gusinu, Monica Bevegni, Gladys Blandino, Alessandra Fozza, Fabrizio Levrero

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefano AgostinelliUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.ORCID https://orcid.org/0009-0001-1834-9513
Daniele ZefiroUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Stefania GarelliUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.ORCID https://orcid.org/0000-0003-1939-409X
Francesca CavagnettoUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.ORCID https://orcid.org/0000-0003-3872-6491
Marco GusinuUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Monica BevegniUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Gladys BlandinoUO Radioterapia Oncologica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Alessandra FozzaUO Radioterapia Oncologica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Fabrizio LevreroUO Fisica Sanitaria, IRCCS Ospedale Policlinico San Martino, Genova, Italy.ORCID https://orcid.org/0000-0003-2199-027X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis work introduces BreastWatch, a Varian Eclipse script tool designed to help medical physicists, dosimetrists, and radiation oncologists easily inspect and improve External Beam Breast Treatment (EBBT) plans using automatic evaluation of protocol dose-constraints enhanced by a Community-Based approach.

methodsBreastWatch examines Eclipse EBBT Plans and Plan Sums, automatically testing the plan's DVH against built-in international EBBT protocol (NRG RTOG1005, ICR Fast-Forward, ICR FAST, and EUROPA 1.2) dose-constraints. Results are displayed using traffic lights and an overall BW-SCORE. To overcome protocol dose-constraints limitations, the script can export plan data and dose values in CSV format to build a Community-Based Plan Library. These data are automatically read back in BreastWatch to check plans against the statistical distribution of similar Community plans and compute a CB-SCORE, which complements the protocol-based BW-SCORE. In this paper, BreastWatch v.1.6.5.0 script's design and strengths are examined and discussed, after extensive testing with more than 800 EBBT plans by six experienced planners. In a preliminary analysis, the usefulness of the CB approach is investigated by examining the chronological series of two dose-constraints values (Contra-Lung V3Gy and Heart Average Dose) before and after its introduction in BreastWatch.

resultsWe found BreastWatch to speed up the EBBT planning process, while at the same time helping to improve the treatment plans in terms of PTVs coverage and uniformity, sparing of OARs, consistency, and robustness among different planners. The preliminary analysis of the chronological series of two dose-constraints values for a subgroup of 68 EBBT plans shows a trend (p-value = 0.07) for values to be improved and more consistent after the CB approach introduction.

conclusionsThe BreastWatch script is a useful tool for the automatic evaluation of Eclipse EBBT plans. BreastWatch and its Community-Based features have been found to be a simple but effective automation approach to improve the EBBT planning process.

Indexed as

Breast NeoplasmsOrgans at RiskRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedSoftwareAlgorithmsFemaleHumansRadiotherapy Dosageautomatic evaluationbreast radiation therapyeclipsescriptingtreatment plan scoring

Identifiers

PMID40170438
PMCPMC12148785

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.