Evidence map›Paper›PMID 40170853›Full record

ArticleFrontiers in immunology2025

Increased long-term central memory T cells in patients with retreatment pulmonary tuberculosis.

Xin Yao, Haomin Cai, Jianxia Chen, Fangyong Yu, Xiaocui Wu, Yarong Shi, Yang Hu, Yuyan Xu, Qinghua Xu, Zhonghua Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin Yao *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Haomin Cai *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Jianxia Chen *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Fangyong YuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaocui WuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yarong ShiShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yang HuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yuyan XuThe Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, China.
Qinghua XuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Zhonghua LiuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: T cells are crucial in controlling Mycobacterium tuberculosis infection and disease progression. Nevertheless, the specific functions and changes of T lymphocyte subsets in retreatment tuberculosis remain poorly understand. The study aims to identify the changes in T lymphocyte subsets and the immunoprotective effect of T Method: We collected venous blood from the participants and assessed using flow cytometry. Univariate analysis and regression model were used to evaluate the changes of T lymphocyte subsets and key subsets in retreatment tuberculosis. Results: In the study, while the frequencies of CD4 and CD8 T cells were similar between primary and retreatment patients, retreatment patients exhibited a significant increase in T Conclusion: Development of adjunct immunotherapies for increasing T

Indexed as

Immunologic MemoryMemory T CellsMycobacterium tuberculosisT-Lymphocyte SubsetsTuberculosis, PulmonaryAdultAntitubercular AgentsCD8-Positive T-LymphocytesFemaleHumansMaleMiddle AgedRetreatmentAntitubercular Agentscenter memory T cellsefficacyimmunotherapiesretreatment tuberculosisT lymphocyte subsets

Identifiers

PMID40170853
PMCPMC11959053

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.