Evidence mapPaperPMID 40171216Full record

ArticleTherapeutic advances in endocrinology and metabolism2025

Triglyceride-glucose index and lipid ratios in women with and without polycystic ovary syndrome: a systematic review and meta-analysis.

Juan R Ulloque-Badaracco, Esteban A Alarcon-Braga, Enrique A Hernandez-Bustamante, Juan C Cabrera-Guzmán, Giuseppe Dotto-Vasquez, Gian F Maldonado-Basurto, Germán Rivera-Cabrera, Sherelym H Maita-Arauco, Andres A Horruitiner-Mendoza, Percy Herrera-Añazco and 2 more

Abstract read
In one paragraph

Article in Therapeutic advances in endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juan R Ulloque-BadaraccoFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Esteban A Alarcon-BragaFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Enrique A Hernandez-BustamanteGrupo Peruano de Investigación Epidemiológica, Unidad para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.
Juan C Cabrera-GuzmánFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Giuseppe Dotto-VasquezFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Gian F Maldonado-BasurtoFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Germán Rivera-CabreraFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Sherelym H Maita-AraucoFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Andres A Horruitiner-MendozaFacultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Percy Herrera-AñazcoFacultad de Ciencias de la Salud, Universidad Privada del Norte, Trujillo, Peru.
Vicente A Benites-ZapataUnidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Avenida La Fontana #550 La Molina, Lima, Peru.ORCID https://orcid.org/0000-0002-9158-1108
Faustino R Pérez-LópezInstituto Aragonés de Ciencias de la Salud, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain.ORCID https://orcid.org/0000-0002-2801-416X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The pathophysiology of polycystic ovary syndrome (PCOS) is complex and heterogeneous. This systematic review and meta-analysis aimed to determine the triglyceride-glucose index and lipid ratios in women with and without PCOS. Methods: Literature searches were performed in PubMed, Scopus, Web of Science, Scielo, and Embase for studies reporting the triglyceride-glucose index and total cholesterol/high-density lipoprotein (HDL)-cholesterol, triglyceride/HDL-cholesterol, and low-density lipoprotein (LDL)-cholesterol/HDL-cholesterol ratios. Results are reported as standardized mean differences (SMDs) along with their 95% confidence intervals (CIs). Results: The search identified 61 observational studies, including case-control ( Conclusion: Patients with PCOS show significantly higher triglyceride-glucose index and total cholesterol/HDL-cholesterol, triglyceride/HDL-cholesterol, and LDL-cholesterol/HDL-cholesterol ratios than those without the syndrome.

Indexed as

glucosehigh-density lipoprotein-cholesterollow-density lipoproteinmeta-analysispolycystic ovary syndrometotal cholesterol/HDL-cholesterol ratiotriglyceride–glucose indextriglyceride/HDL-cholesterol ratio

Identifiers

PMID40171216
PMCPMC11960191

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.