Evidence map›Paper›PMID 40171446›Full record

ReviewMolecular therapy. Nucleic acids2025

Computational approaches for identifying neuropeptides: A comprehensive review.

Roya Rahmani, Leila R Kalankesh, Reza Ferdousi

Abstract readReview
In one paragraph

Review in Molecular therapy. Nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roya RahmaniStudent Research Committee, Tabriz University of Medical Science, Tabriz, Iran.
Leila R KalankeshDepartment of Health Information Technology, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza FerdousiDepartment of Health Information Technology, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropeptides (NPs) are key signaling molecules that interact with G protein-coupled receptors, influencing neuronal activities and developmental pathways, as well as the endocrine and immune systems. They are significant in disease contexts, offering potential therapeutic targets for conditions such as anxiety, neurological disorders, cardiovascular health, and diabetes. Understanding and detecting NPs is crucial because of their complex functions in health and disease. Historically, identifying NPs via wet lab techniques has been time-consuming and costly. However, integrating computational methods has shown the potential to improve efficiency, accuracy, and cost-effectiveness. Computational techniques, such as artificial intelligence and machine learning, have been extensively researched in recent years for the identification of NP. This review explores the application of machine learning (ML) techniques in predicting various aspects of NPs, including their sequences, cleavage sites, and precursors. Additionally, it provides insights into databases containing NP metadata and specialized tools used in this domain.

Indexed as

MT: Bioinformaticsneuropeptide analysisneuropeptide databasesneuropeptide identification toolsneuropeptides

Identifiers

PMID40171446
PMCPMC11960512

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.