Evidence map›Paper›PMID 40172946›Full record

ArticleeLife2025

At the crossroads of calcium signaling, protein synthesis and neuropeptide release.

Jakob Rupert, Dragomir Milovanovic

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jakob RupertLaboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE), Berlin and Bonn, Germany.ORCID https://orcid.org/0000-0002-0879-1594
Dragomir MilovanovicLaboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE), Berlin and Bonn, Germany.ORCID https://orcid.org/0000-0002-6625-1879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Indexed as

Calcium SignalingNeuropeptidesProtein Biosynthesisrab GTP-Binding ProteinsAnimalsCalciumEndoplasmic ReticulumHumansCalciumNeuropeptidesrab GTP-Binding Proteinsendoplasmic reticulumexocytosismouseneuropeptideneuroscienceprotein synthesisRab10synaptic transmission

Identifiers

PMID40172946
PMCPMC11964446

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.