Evidence map›Paper›PMID 40175862›Full record

ArticleDrugs in R&D2025

Comparative Preclinical Evaluation of Tuznue Versus Referent Herceptin: A Registered Trastuzumab Biosimilar.

Herve Bischoff, Neil K O'Connor, Jamie Kim, Bogdan V Popescu, Cecile Bigot, Sumita Pradhan, Rusha Chakraborty, Litha Jaison, Fathima Majeed, Lisa S Park and 4 more

Abstract readComparative Study
In one paragraph

Article in Drugs in R&D, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Herve Bischoff *Institut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France.
Neil K O'Connor *Prestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Jamie KimPrestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Bogdan V PopescuInstitut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France.
Cecile BigotInstitut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France.
Sumita PradhanPrestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Rusha ChakrabortyPrestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Litha JaisonPrestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Fathima MajeedPrestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Lisa S ParkPrestige BioPharma Ltd, 21 Biopolis Road, #04-24 Nucleos South Building, Singapore, Singapore.
Lotfi BoudaliInstitut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France.
Alexandre DetappeInstitut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France.
Xavier PivotInstitut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France. x.pivot@icans.eu.ORCID http://orcid.org/0000-0003-3689-5013
Pierre ColiatInstitut de Cancérologie de Strasbourg - Paul Strauss Cancer Center, 17 rue Albert Calmette, 67033, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe high cost of trastuzumab (Herceptin

methodsMultiple analytical methods were performed to assess key quality attributes of Tuznue

resultsTuznue

conclusionsThe comprehensive analytical characterization confirms the biosimilarity of Tuznue

Indexed as

Antineoplastic Agents, ImmunologicalBiosimilar PharmaceuticalsTrastuzumabAntibody-Dependent Cell CytotoxicityBreast NeoplasmsCell Line, TumorCell ProliferationDrug Evaluation, PreclinicalErb-b2 Receptor Tyrosine KinasesFemaleHumansReceptors, FcAntineoplastic Agents, ImmunologicalBiosimilar PharmaceuticalsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesReceptors, FcTrastuzumab

Identifiers

PMID40175862
PMCPMC12011664

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.