Evidence mapPaperPMID 40176259Full record

ReviewGut microbes2025

Maternal consumption of urbanized diet compromises early-life health in association with gut microbiota.

Rong Huang, Guicheng Zhou, Jie Cai, Cha Cao, Zhenjun Zhu, Qingping Wu, Fen Zhang, Yu Ding

Abstract readReview
In one paragraph

Review in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rong HuangDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0009-0008-9870-049X
Guicheng ZhouDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0000-0002-4183-4306
Jie CaiDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0000-0001-9476-3997
Cha CaoDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0009-0000-3934-3826
Zhenjun ZhuDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0000-0003-0807-4525
Qingping WuGuangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.ORCID 0000-0001-6503-359X
Fen ZhangDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0000-0003-0887-1073
Yu DingDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0000-0002-3688-7294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urbanization has significantly transformed dietary habits worldwide, contributing to a globally increased burden of non-communicable diseases and altered gut microbiota landscape. However, it is often overlooked that the adverse effects of these dietary changes can be transmitted from the mother to offspring during early developmental stages, subsequently influencing the predisposition to various diseases later in life. This review aims to delineate the detrimental effects of maternal urban-lifestyle diet (urbanized diet) on early-life health and gut microbiota assembly, provide mechanistic insights on how urbanized diet mediates mother-to-offspring transfer of bioactive substances in both intrauterine and extrauterine and thus affects fetal and neonatal development. Moreover, we also further propose a framework for developing microbiome-targeted precision nutrition and diet strategies specifically for pregnant and lactating women. The establishment of such knowledge can help develop proactive preventive measures from the beginning of life, ultimately reducing the long-term risk of disease and improving public health outcomes.

Indexed as

DietGastrointestinal MicrobiomeMaternal Nutritional Physiological PhenomenaPrenatal Exposure Delayed EffectsUrbanizationAnimalsFemaleHumansInfant, NewbornPregnancybreast milkearly-life healthgut microbiotaMaternal urbanized dietmetabolometransmission

Identifiers

PMID40176259
PMCPMC11988223

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.