Evidence mapPaperPMID 40176397Full record

ReviewArthritis care & research2025

Metabolic Consequences of Rheumatoid Arthritis.

Stevie Barry, Emily Sheng, Joshua F Baker

Abstract readReview
In one paragraph

Review in Arthritis care & research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Article
  8. Polypharmacy and drug interactions in the management of rheumatoid arthritis.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stevie BarryPerelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0009-0007-4591-1085
Emily ShengPerelman School of Medicine, University of Pennsylvania, Philadelphia.
Joshua F BakerPerelman School of Medicine, University of Pennsylvania and Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.

Funding

Obesity-Induced Inflammatory Mediators Predict Lack of Response in Patients with Rheumatoid Arthritis Starting Biological TherapiesR01AR083584 · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2025 to 2025
$441k
NIAMS NIH HHS R01 AR083584NIAMS NIH HHS R01-AR083584RRD VA I01 RX003644RRD VA I01 RX004770
6 · The paper itself

Abstract

Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long-term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a "lipid paradox," with reduced low-density lipoprotein being associated with higher rates of cardiovascular disease. In this review, we discuss changes to body composition, insulin resistance, lipids, and blood pressure that often occur in patients with RA. We examine the current understanding of the mechanisms underlying disruptions in metabolic pathways in RA, their clinical effects, and how treatment affects these changes.

Indexed as

Arthritis, RheumatoidBlood PressureBody CompositionHumansInsulin ResistanceMetabolic Syndrome

Identifiers

PMID40176397
PMCPMC12500507

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.