Evidence map›Paper›PMID 40177135›Full record

ArticleOncology letters2025

TP53 gene mutation in lymphoepithelioma‑like carcinoma of the breast with thyroid cancer: A case report.

Jie Sun, Jiyue Gao, Jun Li, Haidong Zhao

Abstract readCase Reports
In one paragraph

Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jie SunDepartment of Breast Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China.
Jiyue GaoDepartment of Breast Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China.
Jun LiDepartment of Breast Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China.
Haidong ZhaoDepartment of Breast Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, breast cancer is the most common malignancy among women and thyroid cancer is also one of the common cancer types among women. Patients with breast cancer exhibit a higher incidence of thyroid cancer than that noted in the general population. The exact mechanism of multiple tumors remains elusive. In the present study, the case of a patient with multiple tumors harboring gene mutation is reported. Specifically, a patient with lymphoepithelioma-like carcinoma of the breast (LELC-B) and thyroid cancer is described. It was hypothesized that the short interval between the onset of these two types of malignant tumor may be related to the TP53 gene mutation status of the patient. To date, a specific relationship between gene mutations and multiple tumors is yet to be determined. Therefore, additional studies are required to address this topic.

Indexed as

case reportlymphoepithelioma-like carcinoma of the breastthyroid cancerTP53 gene

Identifiers

PMID40177135
PMCPMC11962588

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.