Evidence mapPaperPMID 40177193Full record

ArticleWorld journal of hepatology2025

Patterns of dietary supplement use among United States patients with steatotic liver disease: Vitamins, minerals and botanicals.

Melinda Wang, Gabrielle Jutras, Giuseppe Cullaro, Anand Dhruva, Jennifer C Lai

Abstract read
In one paragraph

Article in World journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melinda WangDepartment of Internal Medicine, University of California San Francisco, San Francisco, CA 94143, United States.
Gabrielle JutrasDivision of Hepatology, Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montreal H2X 0A9, Quebec, Canada.
Giuseppe CullaroDepartment of Medicine, Division of Gastroenterology and Hepatology, University of California - San Francisco, San Francisco, CA 94143, United States.
Anand DhruvaOsher Center for Integrative Medicine, University of California, California, MD 94143, United States.
Jennifer C LaiDepartment of Medicine, Division of Gastroenterology and Hepatology, University of California - San Francisco, San Francisco, CA 94143, United States. jennifer.lai@ucsf.edu.

Funding

UCSF Liver CenterP30DK026743 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 1986 to 2025
$6.5M
NIDDK NIH HHS P30 DK026743
6 · The paper itself

Abstract

backgroundDietary supplement (DS) usage among United States adults has significantly increased. Patients with steatotic liver disease (SLD) may have unique motivations to take DS in light of their liver condition and co-morbidities.

aimTo characterize DS use in SLD patients and explore motivations for their use.

methodsAdults ≥ 18 years old with complete transient elastography and dietary data from the National Health and Nutrition Examination Survey between January 2017 and March 2020 were studied. SLD was defined using consensus criteria, combining clinical indicators with elastography thresholds. The DS Questionnaire (DSQ) was used to record participants' use of DSQ. Sample weights were applied to estimate national prevalence.

resultsOf 2413 participants with SLD, 1058 reported using DS, for an estimated prevalence of 44.8% [standard error (SE) 2.4] with an average of 2.6 (SE 0.2) DS per person. Among SLD participants taking DSQ, 53.2% (SE 3.3) reported using non-vitamin/non-mineral ones, with an average of 1.8 (SE 0.1) such supplements per person. DS users were more likely to be female, have higher levels of education, and have greater food security (P < 0.02 for all). The most common motivations for using DS were to follow doctor's advice (36.7%, SE 1.8), to improve overall health (22.1%, SE 2.0), and to maintain health (19.2%, SE 1.9).

conclusionNearly half of individuals with SLD report taking DS. This study underscores the pressing need to deepen our understanding of DS use/motivations to develop tailored patient counseling strategies.

Indexed as

BotanicalDietary supplementDisparityNational Health and Nutrition Examination SurveySteatotic liver disease

Identifiers

PMID40177193
PMCPMC11959662

What Socratic holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.