Evidence map›Paper›PMID 40177240›Full record

ArticleFrontiers in oncology2025

Metastatic MiT family/TFE translocation renal cell carcinoma in adults: case series reports and literature reviews.

Xueru Sun, Hong Wang, XiuYue Man, Chen Chen, XiaoFeng Cong, Jing Zhang, Lei Yang

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xueru SunDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Hong WangDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
XiuYue ManDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Chen ChenDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
XiaoFeng CongDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Jing ZhangDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Lei YangDepartment of Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article presents a case study of three patients diagnosed with MiT/TFE tRCC at our hospital. The tumors were located in the left kidney of all three patients, with two of them being under 30 years old. Within a short timeframe, two of all patients developed liver metastases. Genetic testing was conducted in one case, FISH testing in another, and all cases underwent a combination of targeted therapy and immunotherapy. By analyzing the clinical, pathological, and genomic characteristics of these patients, this article aims to enhance the understanding of MiT family translocation renal cell carcinoma, as well as improve the diagnosis, treatment, and prognosis of this rare form of renal cell carcinoma. Further evidence is provided to support these findings.

Indexed as

biological behaviorclinical managementgenetic mutationMit family translocation renal cell carcinoma (MiT/TFE tRCC)molecular characterizationtargeted therapy

Identifiers

PMID40177240
PMCPMC11961414

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.