Evidence map›Paper›PMID 40177410›Full record

ArticleFrontiers in neurology2025

Association between the hemoglobin-to-red cell distribution width ratio and three-month unfavorable outcome in older acute ischemic stroke patients: a prospective study.

Luwen Huang, Linlin Li, Qing-Rong Ouyang, Ping Chen, Ming Yu, Lei Xu

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luwen Huang *Department of Neurology, Suining Central Hospital, Suining, Sichuan Province, China.
Linlin Li *Department of Neurology, Suining Central Hospital, Suining, Sichuan Province, China.
Qing-Rong OuyangDepartment of Neurology, Suining Central Hospital, Suining, Sichuan Province, China.
Ping ChenDepartment of Pharmacy, Suining Central Hospital, Suining, Sichuan Province, China.
Ming Yu *Department of Neurology, Suining Central Hospital, Suining, Sichuan Province, China.
Lei Xu *Department of Neurology, Suining Central Hospital, Suining, Sichuan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Acute ischemic stroke (AIS) is a prevalent acute condition among older individuals. This study is the first investigation of the link between the HRR and unfavorable three-month outcome in older AIS patients. Methods: This secondary research used data from a sample of 1,470 older AIS patients collected from a South Korean hospital between January 2010 and December 2016. Multiple imputation was applied to account for absent values. Binary logistic regression analysis was used to examine the relationship between the baseline HRR and adverse outcome at three-month. Restricted cubic spline analysis was employed to evaluate the correlation between HRR levels and adverse outcome. Interaction tests were performed to discern variations among subgroups. Results: At 3 months, the overall incidence of adverse events was 31.43%, with a median HRR of 9.49. Compared to those with a lower HRR (Q1), the adjusted odds ratios (ORs) for the HRR in Q2, Q3, and Q4 were 0.61 (95% CI: 0.41-0.92, Conclusion: A lower HRR was correlated with a higher risk for adverse outcome in older AIS patients.

Indexed as

acute ischemic strokeassociationhemoglobin-to-red cell distribution width ratioolder participantsprognosis

Identifiers

PMID40177410
PMCPMC11963698

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.