Evidence map›Paper›PMID 40177487›Full record

ArticleFrontiers in microbiology2025

Haohao Sun, Yaqing Liu, Yiping Huang, Kangjun Xiong, Zhendong Zhang, Weishan Wang, Yi Dai, Jing Li, Qi Li, Sibo Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haohao Sun *The First Affiliated Hospital of Shihezi University, Shihezi, China.
Yaqing Liu *The First Affiliated Hospital of Shihezi University, Shihezi, China.
Yiping HuangThe Medical College of Shihezi University, Shihezi, China.
Kangjun XiongThe Medical College of Shihezi University, Shihezi, China.
Zhendong ZhangThe First Affiliated Hospital of Shihezi University, Shihezi, China.
Weishan WangThe First Affiliated Hospital of Shihezi University, Shihezi, China.
Yi DaiThe First Affiliated Hospital of Shihezi University, Shihezi, China.
Jing LiThe First Affiliated Hospital of Shihezi University, Shihezi, China.
Qi LiThe First Affiliated Hospital of Shihezi University, Shihezi, China.
Sibo WangXi'an Jiaotong University Affiliated Honghui Hospital, Xi'an, China.
Chenhui ShiThe First Affiliated Hospital of Shihezi University, Shihezi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Osseous echinococcosis, caused by Methods: In vitro, a co-culture system of Results: PSCs significantly enhanced osteoclast differentiation and bone resorption, upregulated osteoclast markers (CTSK, NFATc1), and activated MAPK signaling. DUSP4 overexpression reversed these effects, reducing osteoclast activity and MAPK phosphorylation. In vivo, PSC infection caused severe bone destruction, which was mitigated by DUSP4 overexpression. Disscussion: This study reveals the molecular mechanism by which

Indexed as

boneDUSP4Echinococcus granulosus (E. granulosus)MAPKosteoclast

Identifiers

PMID40177487
PMCPMC11961949

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.