Evidence map›Paper›PMID 40177524›Full record

ArticleBiology methods & protocols2025

A generalized protocol for the induction of M2-like macrophages from mouse and rat bone marrow mononuclear cells.

Ulugbek R Yakhshimurodov, Kizuku Yamashita, Kenji Miki, Takuji Kawamura, Shunsuke Saito, Shigeru Miyagawa

Abstract read
In one paragraph

Article in Biology methods & protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Regenerative therapy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ulugbek R YakhshimurodovDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, 565-0871, Japan.ORCID https://orcid.org/0009-0004-0732-2261
Kizuku YamashitaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, 565-0871, Japan.
Kenji MikiPremium Research Institute for Human Metaverse Medicine (PRIMe), Osaka University, Suita, 565-0871, Japan.
Takuji KawamuraDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, 565-0871, Japan.
Shunsuke SaitoDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, 565-0871, Japan.
Shigeru MiyagawaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regardless of origin and localization, macrophages are the major immune cells that maintain homeostasis in both healthy and diseased states. However, there is no consensus on the phenotypes, functions and fates of macrophages. Existing studies clarify macrophage biology from different biomedical research perspectives, but the heterogeneity of induction methods hinders reproducibility and comparability. To address this problem, we validated a novel generalized

Indexed as

M2macrophagemouseprotocolrat

Identifiers

PMID40177524
PMCPMC11964487

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.