Evidence map›Paper›PMID 40177932›Full record

ArticleCurrent eye research2025

Design, Production and Study of Flexible Acrylic Keratoprosthesis.

Victoria H Fan, Michael G Sun, Ahmed F Al-Qahtani, Ibraim V Vieira, Charles Q Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current eye research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Victoria H FanDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Michael G SunDepartment of Ophthalmology, Illinois Eye and Ear Infirmary, University of Illinois Chicago, Chicago, IL, USA.
Ahmed F Al-QahtaniDepartment of Ophthalmology, Illinois Eye and Ear Infirmary, University of Illinois Chicago, Chicago, IL, USA.
Ibraim V VieiraDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Charles Q YuDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI TIRIN MOORE · 2017 to 2026
$8.0M
Minimally Invasive KeratoprosthesisK08EY027459 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YU, CHARLES · 2017 to 2020
$857k
NEI NIH HHS K08 EY027459NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

purposeTo design, produce and implant one-piece flexible acrylic keratoprostheses for the treatment of corneal blindness.

methodsA protocol was developed to produce flexible acrylic sheets of differing properties, and their mechanical characteristics were evaluated. To assess

resultsFlexible acrylic copolymer sheets of high clarity were produced by free radical polymerization. Their mechanical properties and refractive indices could be altered with different material formulations. They demonstrated no

conclusionsMolding of flexible acrylic allows for production of one-piece keratoprostheses of a complex shape and opens new possibilities for the treatment of corneal blindness.

Indexed as

Acrylic ResinsBlindnessCorneaCorneal DiseasesProstheses and ImplantsProsthesis DesignAnimalsDisease Models, AnimalHumansPilot ProjectsPrinting, Three-DimensionalProsthesis ImplantationRabbitsAcrylic Resinsacrylicartificial corneainjectionKeratoprosthesismolding

Identifiers

PMID40177932
PMCPMC12187538

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.